medRxivLeveraging diffusion-based synthetic data to improve diagnostic classification of structural heart disease
This study explores diffusion-based generative modeling using a Denoising Diffusion Probabilistic Model (DDPM) framework to conditionally synthesize chest X-rays from echocardiographic measurements and demographic features. We evaluate whether synthetic images produced by the model can enhance the performance of a diagnostic convolutional neural network in detecting structural heart disease across varying combinations of real and synthetic data.